For patients with ACS, the higher preferred Hb threshold of 9 g/dL (8–9.6) is in accordance with the transfusion guideline from the National Institute for Health and Care Excellence (NICE, 2018), in which a Hb threshold (8–10 g/dL) for patients with symptomatic coronary disease is advised. Here, GSTM1 is linked to coronary artery disorder.