The results showed that interference with FUBP1 inhibited the proliferation of NB cells (SK-N-BE(2)-EV = 1.90 ± 0.05; SK-N-BE(2)-shFUBP1 = 1.51 ± 0.13; n = 12; p < 0.001), while the additional administration of 2-DG could block the effect of FUBP1 on the proliferation of NB (SK-N-BE(2)-EV = 1.32 ± 0.07; SK-N-BE(2)-shFUBP1; n = 12; NS; Fig. 4a). Here, FUBP1 is linked to neuroblastoma.