Pathway enrichment analysis for genes that were commonly up-regulated between NASH, NASH-CH, and human NASH showed that 29 gene sets including phosphoinositide 3-kinase (PI3K), interleukin 7 (IL7), cell death signaling, and platelet-derived growth factor (PDGF) were among the most significant dysregulated pathways (Figure 6A). Here, IL7 is linked to metabolic dysfunction-associated steatohepatitis.