We observed significant over-expression of ADAR, ADARB1, DDX5/17/20, DGCR8, DICER1, DROSHA, EIF2C1-4 (AGO1-4), GEMIN4, POLR2A, TARBP2, TNRC6A and XPO5 in tumor tissue compared to adjacent mucosa. This evidence concerns the gene POLR2A and neoplasm.