A molecular docking analysis has been performed on diketone form of curcumin molecule with acetylcholinesterase (AChE), indicating that this molecule exhibits a large binding affinity, and suggesting the use of curcumin to inhibit AChE and balance the level of acetylcholine as an alternative to the present Alzheimer’s disease treatments [176]. The gene discussed is ACHE; the disease is early-onset autosomal dominant Alzheimer disease.