The finding of significantly higher levels of TNF-α in agitated patients when compared to non-agitated patients was also replicated in a subgroup analysis where the psychosis group was excluded (22.84 ± 18.23 vs 15.31 ± 19.22, Mann-Whitney U = 4841.0, d = 0.13, p = 0.025) (Fig 3). The gene discussed is TNF; the disease is psychotic disorder.