CD28 and neoplasm: In order to enhance the localization of nanoparticles at tumors, Chiang et al. synthesized fucoidan and dextran‐based super‐paramagnetic iron oxide nanoparticles functionalized with anti‐PD‐L1 Ab and anti‐CD3/anti‐CD28 Ab on the surface.129 With magnetic navigation, higher tumor accumulation of nanoparticles was achieved and off‐target effect was evidently averted.