1. Pathology showing focallymphocytic sialadenitis with afocus score ≥ 1 (worth 3 points)2. Positive anti-Ro/SS-A antibodies(worth 3 points)3. SICCA ocular staining score ≥ 5 orRose Bengal score ≥ 4 by the vanBijsterveld scoring system (worth1 point)4. Schirmer I test ≤ 5 mm per 5 min(worth 1 point)5. Unstimulated whole salivary flowless than 0 ≤ 0.1 mL/min (worth 1point). This evidence concerns the gene CALR and sialadenitis.