Although it was difficult to validate which TF can directly bind the PRE1 SNP due to insufficient ChIP-seq data in T/NK cells, we found the PRE1 candidate SNP rs11227311 to be located within a weak TCF3 ChIP-seq peak in Kasumi1 acute myeloid leukemia cell line [GEO GSE43834 (Sun et al., 2013)] (Figure 3B; Materials and Methods). Here, TCF3 is linked to acute myeloid leukemia.