Random GH, IGF-1 SDS, GH inhibition ratio, tumor volume, Knosp grade, tumor consistency, and P53 value were selected (according to their AIC values) as discriminatory factors to build the clinical model, which resulted in the AUC value being improved to 0.86 (Figure 2B), with an optimized ACC of 0.807, sensitivity of 0.844, and specificity of 0.76 (Table 2). This evidence concerns the gene IGF1 and neoplasm.