IL1A and cardiovascular disorder: The IL-1 family of ligands and receptors are associated with both acute and chronic inflammation (Gabay et al., 2010; Dinarello, 2011), and IL-1α is an intracellular cytokine involved in various immune responses and inflammatory processes (Schett et al., 2016), that is known to be upregulated in cardiovascular diseases (Pfeiler et al., 2017).