KCNE1 and familial long QT syndrome: In addition, the Sanger sequencing results showed that no mutations in major ion channels and transporters such as KCNQ1 (codes for the α subunit of the slowly activating IKs channel), KCNE1 (codes for the β subunit of the IKs potassium channel), KCNH2 (codes for the α subunit of the rapidly activating IKr channel) or KCNE2 (codes for the β subunit of the IKr potassium channel) or other channel-related LQTS genes were identified.