We also evaluated αGlcNAc expression in human gastric adenocarcinoma and pyloric gland adenoma, which precedes gastric adenocarcinoma, and observed frequent loss of αGlcNAc expression in MUC6-positive differentiated-type adenocarcinoma and high-grade pyloric gland adenoma22,23,25. This evidence concerns the gene MUC6 and adenocarcinoma.