Kaplan–Meier analysis indicated that MPS-1 over-expression was correlated with poor OS in obese CRC patients (P = 0.038, Fig. 2b) instead of non-obese cases (P > 0.05, Fig. 2c), which might contribute to the statistical insignificance in survival analysis of all patients (P > 0.05, Fig. 2d). Here, RPS27 is linked to colorectal carcinoma.