GAPDH and acute lymphoblastic leukemia: Moreover, inhibition of glycolysis by glycolytic inhibitors, such as 3-Bromopyruvate (3-BP), 2-deoxy-d-glucose (2-DG), lonidamine (LND) or the down-regulation of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) through RNA interference leads to sensitization of prednisolone-resistant ALL cell lines to glucocorticoids [12].