In order to directly test the impact of p53 on PD-L1 expression, we generated several cell lines with inducible shRNA targeting TP53. Two TP53-wt NSCLC cell lines, i.e. A549 and H460, which in another study demonstrated increased PD-L1 expression upon p53 knockdown or miR-34a transfection, served as positive controls [27]. Here, CD274 is linked to non-small cell lung carcinoma.