PNPLA3 and metabolic dysfunction-associated steatotic liver disease: In fact, after adjustments for potential confounders, NAFLD, but not the PNPLA3 G allele, emerged as being independently associated with eGFR < 90 mL/min/1.73 m2 and/or albuminuria > 30 mg/24 h, conferring a 4.5-fold risk of abnormal renal function.