PNPLA3 and metabolic dysfunction-associated steatotic liver disease: As shown in Figure 3A, children with NAFLD and the PNPLA3 CG + GG genotype had 12% lower eGFR values than those with NAFLD and the PNPLA3 CC genotype (115.6 ± 24.1 mL/min/1.73 m2 vs. 131.4 ± 25.3 mL/min/1.73 m2; p = 0.003).