However, it should be mentioned that G*01:01:01:01/UTR-1 was associated with a higher soluble HLA-G production [28] or with a high HLA-G production in specific tumor or embryonic stem cell lines [31,42], and thus it is not clear whether this haplotype would be also related to this increased production in different microenvironments such as the skin and melanocytes. Here, HLA-G is linked to neoplasm.