Additionally, kaempferol was administrated in human embryonic kidney (HEK)293 cells with various effects including the reduction of TNF-induced IL-8 activity, the genetic expression of IL-8, blocking NF-κB activity, and lowering ROS production [116], and this may be useful to reduce inflammation and thereby lower susceptibility to breast cancer. This evidence concerns the gene CXCL8 and breast carcinoma.