GSTM1 and breast carcinoma: Although the CCND1 genotype was not associated with breast cancer risk, when analysed together with ω3 fatty acid consumptions, there was an association between risk, particularly advanced disease, and a high intake of ω6, a low intake of ω3, genotype (CCND1 GA ) or a complete lack of GSTT1 or GSTM1 activity [52].