Aged garlic extracts have been shown to increase cytokine release such as IL-2, IL-12 and tumour necrosis factor alpha (TNFα), reactivating lymphocyte proliferation, macrophage phagocytosis, the infiltration of lymphocyte and macrophage into cancer cells, and stimulating NF-κB activity [103,104,105,106]. This evidence concerns the gene NFKB1 and cancer.