In a colorectal cancer mouse xenograft model, PTH decreases tumor volume, tumor weight, microvessel density in tumor tissues; and the expressions of angiogenic factors, including iNOS, eNOS, VEGFR2, VEGF-A, bFGF, and basic fibroblast growth factor (bFGFR) [46]. The gene discussed is FGF2; the disease is neoplasm.