In alcoholic and high-fat diet-induced alcoholic fatty liver rats, PTH improves hepatic function defects, hepatic pathology, and impairment in lipid metabolism by inhibiting the homocysteine-related protein kinase RNA-like endoplasmic reticulum kinase (PERK)/eukaryotic translation initiation factor 2α (eIF2α) pathway [57]. The gene discussed is EIF2A; the disease is Hepatic steatosis.