NLRP7 and hydatidiform mole: In addition, NLRP7 is referred to as a maternal-effect gene, whose mutations commonly result in recurrent hydatidiform moles (RHMs), a gestational trophoblastic disease characterized by a mass exhibiting trophoblastic hyperplasia and swelling of chorionic villi as well as impaired embryonic development (Murdoch et al. 2006, Sebire et al. 2013, Nguyen et al. 2014, Carey et al. 2015, Ito et al. 2016, Sills et al. 2017, Kalogiannidis et al. 2018).