MGLL and Cholestatic liver disease: Recently, our work investigated the effect of MGL deficiency on liver fibrosis development.12 Interestingly, lack of MGL promoted fibrosis regression due to autophagy‐mediated anti‐inflammatory properties in macrophages.12 Furthermore, Cao et al. showed that global genetic and pharmacological inhibition of MGL protects against inflammation and liver lesions induced by ischemia/reperfusion injury.13 However, the specific role of MGL and its metabolites as potential drivers of cholestatic liver diseases such as PBC and PSC is unknown.