For instance, the deletion of HIC-1, never found mutated in the dataset under analysis but spotted as linker in 15 subjects, has been demonstrated to promote BC (Cheng et al., 2014; Wang et al., 2018); FYN has been proposed as a prognostic marker in ER+ BC (Elias and Ditzel, 2015) and promotes mesenchymal phenotypes of basal types BC cells (Lee et al., 2018). The gene discussed is HIC1; the disease is breast cancer.