FOXA2 and neoplasm: The two remaining MRs belong to the forkhead box (FOX) gene superfamily, which is described controlling several important biological processes,67 including airway epithelial differentiation and branching.68 Several studies observed the tumor suppressor potential of FOXA2 (forkhead box transcription factor A2) in lung cancer through inhibition of EMT, metastasis, and proliferation.69, 70, 71, 72 Accordingly, our study shows that the inferred activity of FOXA2 is repressed in tumor samples.