For example, ATOH8 (atonal Homolog 8) belongs to a group of basic‐helix‐loop‐helix (bHLH) transcription factors involved in the regulation of cardiovascular development, hematopoiesis, skeletal muscle development, neurogenesis, and embryogenesis.35 Dysregulation of this TF was identified with malignant phenotype in several types of cancer.35, 36 However, its exact role in cancer development remains unclear. The gene discussed is TF; the disease is cancer.