More than 150 disease‐causing TTR mutations associated with highly variable clinical manifestations have been identified.2 Val30Met (V30M) is the most frequent mutation worldwide.2, 3 V30M TTR‐FAP typically presents by a slowly progressive polyneuropathy with the onset at around 30 years and most patients could still walk independently even after 20 years of disease onset. This evidence concerns the gene TTR and polyneuropathy.