Survival analysis revealed a statistically significantly prolonged survival of mice following TRAIL delivery in HSCs (mean [SD] = 19 [3.4] vs 15 [2.0] days for MMP14: TRAIL vs MMP14: GFP; two-sided P = .006) (Figure 7E), together with increased Tnsf10 (TRAIL gene) expression in brain tumors as determined by qPCR (Figure 7F). The gene discussed is MMP14; the disease is brain neoplasm.