AXL and renal cell carcinoma: We then knocked down lncRNA7 and lncRNA2/5 in OSRC-2 cells and results revealed that suppressing these lncRNAs decreased the AXL mRNA expression (Fig. 3e), with increased RCC sensitivity to sunitinib by 55% at 10 μM (lncRNA7) and 38% at 10 μM (lncRNA2/5) (Fig. 3f, g).