Conversely, the frequencies of CD28null and CD57+ T cells in the CD8+ T cell population were not significantly different between the HF and control groups (CD8+CD28null T cell fraction: 38.3 ± 17.5% vs. 32.7 ± 12.1%, p = 0.118; CD8+CD57+ T cell fraction: 34.8 ± 14.7% vs. 31.8 ± 12.0%, p = 0.338; Fig. 2d,e). The gene discussed is CD8A; the disease is hydrops fetalis.