Men with RA were divided into 2 groups according to TLR7 CN results by qPCR (Fig. 5), a group A of 6 men with normal TLR7 CN (<1.11) (Fig. 5a) and a group B of 9 men with high TLR7 CN (≥1.11) (Fig. 5b). The gene discussed is TLR7; the disease is rheumatoid arthritis.