TLR7 and rheumatoid arthritis: It is to be noted that by FISH we found at best 1.4% of cells with a supernumerary X Chr, while by TLR7/8 qPCR men with RA who had high TLR7 CN had a mean of 1.20 copies compared to men with normal CN, which corresponds to about 8% of cells with 2 copies (cf results).