We further divided the 70 samples into high (above the median, n = 35) and low (below the median, n = 35) PN-1 expression groups, and explored the correlation between PN-1 expression and the clinicopathological factors, and found the PN-1 mRNA level was positively associated with tumor grade, tumor size, tumor histological, and lymph node metastasis (Table S4; Fig. 1h). Here, SERPINE2 is linked to neoplasm.