MYC and lymphoma: Similarly, lymphoma cell lines that have a MYC translocation and a high level of Myc protein (Fig. 1B) are sensitive to Omomyc, with a 50% effective concentration (EC50) range of 0.4 to 1.1 μM, whereas lymphoma cell lines with low MYC RNA and low Myc protein levels (Fig. 1B) are insensitive to Omomyc (Table 1).