TNFRSF8 and anaplastic large cell lymphoma: CD30 is a tumor necrosis factor (TNF) receptor superfamily member, characteristically expressed on the surface of Reed–Sternberg cells in Hodgkin lymphoma (HL) [49], anaplastic large cell lymphoma (ALCL) cells, and a subset of cutaneous T cell lymphoma (CTCL) cells, with limited expression on normal cells [50].