A multicenter phase II trial (ROMULUS, NCT01691898) randomized 81 patients with R/R DLBCL and 42 patients with R/R FL to receive rituximab plus either Pina (R-Pina) or polatuzumab vedotin (anti-CD79b ADC, discussed above). The gene discussed is CD79B; the disease is diffuse large B-cell lymphoma.