The univariate model included: The male gender, age, body mass index, hypertension, diabetes, dyslipidaemia, chronic kidney disease, chronic obstructive pulmonary disease, OSAS, hyperthyroidism, hypothyroidism, type of arrhythmia, NYHA class on admission and at discharge, heart rate on admission and at discharge, BNP on admission and at discharge, Troponin I on admission and at discharge, LVEF on admission and at discharge, iLAV, rate or rhythm control (dummy variable) and pharmacological treatment at discharge (with each drug class from Table 2 considered as a separate variable). The gene discussed is NPPB; the disease is hyperthyroidism.