Overexpression of SOX11 in a transgenic mouse model (Eμ-SOX11-EGFP) led to enhanced BCR signaling in murine B-cells and induced oligoclonal B-cell hyperplasia in the spleen with an immunophenotype (CD5+CD19+CD23−) identical to human MCL [70]. The gene discussed is CD5; the disease is mantle cell lymphoma.