POU5F1 and Familial prostate cancer: To test how effectively the SORE6 reporter system identifies prostate cells overexpressing SOX2/OCT4, we transduced three prostate cancer cell lines (22Rv1, DU145 and PC3) with lentiviruses encoding the SORE6-GFP reporter, at the same multiplicity of infection (~1), and selected stably expressing lines with puromycin.