As shown in Figure 3, we identified variability in expression of GPR18 across the cell lines with highest expression in the JAR cell line, which exhibited approximately 5 to 6-fold increased transcript level expression over NTERA (human testicular-derived cell line) and Huh-7 (human hepatocellular carcinoma) and ~2-fold increase over the HepG2 (human hepatocellular carcinomas) cell line. Here, GPR18 is linked to hepatocellular carcinoma.