MALAT1 and cancer: Actually, MALAT1 SNPs were reported to be associated with the risk or progression of several cancer types and expression of MALAT1. For example, the AG genotype or G allele of MALAT1 rs619586 SNP was reported to be associated with decreased risks of breast cancer, colorectal cancer (CRC), and papillary thyroid cancer (PTC) and a decreased expression level of MALAT1 [20,21,22].