APOE and atherosclerosis: For example, consumption of pomegranate juice concentrate, a source of potent tannin and anthocyanin antioxidants, reduces oxidative damage markers in diabetic patients [11] and also lowers vascular oxidative stress and attenuates atherosclerosis in SR-B1 (scavenger receptor class b type 1)/ApoE (apolipoprotein E) double KO mice [12].