CD79A and infection: In that regard, sIgA is the predominant Ig isotype in human saliva (Brandtzaeg, 2007, Brandtzaeg, 2013), and a dramatic increase of IgA secretion as well as IgA-positive cells in the salivary gland occurs following infection with pathogens, including the HIV virus (Lu and Jacobson, 2007), the bacteria S. mutans (Colombo et al., 2016), and the parasite toxoplasma gondii (Loyola et al., 2010).