PLA2R1 and chronic kidney disease: Therefore, measurement of PLA2R1-ab is helpful for the management of patients with MN [13] but the significance of PLA2R1-ab levels for renal endpoints, such as doubling of serum creatinine or development of end-stage renal disease, is not clear because of the retrospective character of the available studies or the short-term follow-up of the patients [14, 15].