Fig 6B shows that hnRNP levels were relatively constant between 1–6 hours post-infection and began to decline 7 hours post-infection, when the proteolytic cleavage product was first detected. It is during the late times post-infection, 16–24 hours, that hnRNP A1 fell to its lowest levels (Fig 6B), apaf-1 reached its highest levels (compared to time-zero; Fig 6B), and virus reached its highest titers (~8–9 x 108 pfu/ml). This evidence concerns the gene APAF1 and infection.