The overall analyses suggested no significant association between the MMP-2 -753C>T polymorphism and periodontitis susceptibility in all genetic models (allele model: T vs. C, OR=0.940, 95% C=0.780–1.132, P=0.513; heterozygote model: TC vs. CC, OR=0.985, 95% CI=0.776–1.249, P=0.898; homozygote model: TT vs. CC, OR=0.827, 95% CI=0.486–1.406, P=0.482; dominant model: TT+TC vs. CC, OR=0.844, 95% CI=0.574–1.242, P=0.391 (Fig. 2C); and recessive model: TT vs. TC+CC, OR=0.828, 95% CI=0.492–1.394, P=0.477). Here, MMP2 is linked to periodontitis.