CDKN1C and Adrenal insufficiency: More recently, SNVs in the PCNA-binding domain of CDKN1C have been reported in families with maternally-inherited fetal growth restriction (FGR)without adrenal insufficiency and in familial Silver-Russell syndrome (SRS) (OMIM180860) (Brioudeet al., 2013;Kernset al., 2014;Sabiret al., 2019).