However, 15 out of 32 HCC patients (47%) showed a CD8+ T-cell response against the HLA-A*02-restricted MAGE-A3271 and 7 out of 18 HCC patients (39%) a response against the HLA-A*03-restricted MAGE-A196 epitope (Figure 1A). Here, CD8A is linked to hepatocellular carcinoma.