CD8A and hepatocellular carcinoma: In the case of MAGE-A196-specific CD8+ T-cell responses, the detection rate was somewhat, but not significantly, lower in HD compared to the HCC and liver cirrhosis cohorts (30% versus 53% (cirrhosis), and 39% (HCC)), however, the frequencies of detectable CD8+ T-cell responses were in the same range (Figure 1C).