Yoon et al. 2011 [37] compared the expression patterns of immunohistochemical markers in 10 cases of ameloblastoma and 7 cases of ameloblastic carcinoma, with observation that AC showed a statistically significant higher value in the expression of CK18, parenchymal MMP-2, stromal MMP-9 and Ki-67, in comparison to Ameloblastoma. This evidence concerns the gene KRT18 and ameloblastic carcinoma.