At present, most of the research on TRPV1 is basic science research; only a few studies have clinical relevancy, and research on TRPV1 has mainly focused on chronic pain, while fewer studies have been conducted on its role in other diseases, such as ulcers, hypertension, and some pathological processes, such as airway remodeling and myocardial ischemia. This evidence concerns the gene TRPV1 and ulcer disease.