As a member of the UTP14 family, UTP14a is also involved in ribosome biogenesis and 18S rRNA synthesis.7, 8 Some studies found that the expression of UTP14a is upregulated in human hepatocellular carcinoma and colorectal carcinoma, and it may be associated with poor prognosis.12, 13. This evidence concerns the gene UTP14A and hepatocellular carcinoma.