Univariate logistic regression analysis indicated that the significant variables for tumour size were UPP1 expression (OR = 2.468, 95% CI 1.605‐3.794, P < .001), clinical stage (OR 9.486, 95% CI 6.067‐14.830, P < .001), age (OR 1.943, 95% CI 1.238‐3.049, P = .004), gender (OR 0.551, 95% CI 0.362‐0.838, P = .005) and lymph node metastatic (OR 2.672, 95% CI 1.809‐3.947, P < .001). This evidence concerns the gene UPP1 and neoplasm.