UPP1 and metastatic malignant neoplasm in the lymph nodes: The result of examining the expression of UPase in 72 patients with oral squamous cell carcinoma (SCC) suggests that UPase expression levels were correlated with lymph node metastasis and indicates higher levels of UPase could be a symbol of metastatic phenotype.11 This gives us a hint that UPP1 could be a new potential molecular marker in oncogenesis.