LPXN has been reported to form fusion transcripts in AML by translocation and induce leukemogenesis.50, 51ABLIM2 (actin binding LIM protein family member 2) the host gene of PYK4_f_8090605 had an overall low expression level, with the highest expression in TFH cells (1.6 TPM). The gene discussed is ABLIM2; the disease is acute myeloid leukemia.