Our population-based data are in somewhat contrast to a recent large study by Dickson et al., based on a material from a referral-based institution [9], where subjects with low AD pathology were divided into groups, of which “diffuse Lewy body disease” (n = 33, median Braak NFT stage III, Thal phase 1) was associated significantly with APOE ε4, while no association was found in “transitional Lewy body disease” (n = 46, median Braak NFT stage II, Thal phase 1). The gene discussed is APOE; the disease is Lewy body dementia.